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Antabuse covers to antialcoholic means. Medicine’s action is based on blockade acetaldehyde dehydrogenase, which is involved in the metabolism of ethanol. This leads to increased concentrations of the metabolite of ethanol - acetaldehyde, which causes negative feelings (flushing, nausea, vomiting, tachycardia, lowering blood pressure, etc.), that make it extremely unpleasant alcohol after taking preparation. This leads to a conditioned reflex aversion to the taste and smell of alcoholic drinks. Following oral administration of disulfiram absorbability from the gastrointestinal tract varies from 70 to 90%, is rapidly metabolized, rebounding to dithiocarbamate, which is output in the form of glucuronyl conjugate or is converted into diethylamine and sulfide carbon, its part (4-53%) is excreted through the lungs. The duration of the oral tablets is 48 hours. Generally patients prefer to purchase Antabuse 500mg 120 pills online today. People are prescribed the medicament under therapy and prevention of chronic alcoholism relapse. Patients should be warned of the dangers of intolerance reactions alcoholic drinks. In the case of co-administration with oral anticoagulants is necessary to carry out more frequent monitoring of prothrombin content and correction doses of anticoagulants, which is associated with increased bleeding. Taking alcohol during treatment with the drug patient may get collapse, cardiac arrhythmias, angina, myocardial infarction, cerebral edema, brain hemorrhage. The therapy should not be given because of the possibility of development of mental disorders. In pharmacy you are possible to buy Antabuse online.