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Cordarone relates to class III antiarrhythmic means. The antiarrhythmic effect is due to an increase in phase 3 of the action potential, mainly due to the current reduction of potassium through the channels of the cell membranes of cardiomyocytes, and a decrease in sinus automatism (which leads to bradycardia, unresponsive to atropine effects). The main active substance is Amiodarone. The medicines are blocking a- and b-adrenergic receptors. This preparation also increases the refractory period and decreases the excitability of myocardium. It slows conduction of excitation and prolongs the refractory period of additional atrioventricular pathways. The medicament Cordarone 200mg 180 pills treat and prevent paroxysmal arrhythmias: a life-threatening ventricular arrhythmia, ventricular fibrillation (including after cardioversion), supraventricular arrhythmias, including paroxysm flicker and flutter, atrial and ventricular premature beats, angina. Contraindications include violations of atrioventricular and also intraventricular conduction, sick sinus syndrome excluding cases of correction artificial pacemaker, dysfunction of the thyroid gland (hypothyroidism), cardiac failure (decompensation), hypokalemia, pregnancy, children's age (18 years) (efficacy and also safety have not been established), interstitial lung disease. Before therapy it is necessary to carry out X-ray examination of the lungs, to evaluate the function of the thyroid gland (the concentration of hormones), liver (transaminase activity) and the concentration of plasma electrolytes. Before you buy Cordarone online you need to get a doctor’s examination or other qualified consultation from specialists.