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Coreg covers to non-selective beta-adrenergic blockers. This medication has no intrinsic sympathomimetic activity. It reduces total atrial load by selectively blocking alpha-adrenoceptor. The main active matter is Carvedilol. There is observed suppression of the renin-angiotensin system of the kidney (reduction of plasma renin activity) decrease in blood pressure, heart rhythm and also cardiac output. Blocking alpha-receptors, this medical remedy expands peripheral vessels, thereby decreasing vascular resistance. The concentration in the blood plasma is proportional to the dose. Nowadays for sick patients it becomes not difficult to purchase Coreg 25mg 360 pills on-line. This preparation slightly reduces heart rate, while maintaining renal blood flow and renal function. There is no effect on blood cholesterol levels, and the concentration of potassium, sodium and magnesium. The medicine’s main application is arterial hypertension, angina (stable), chronic cardiovascular failure. The dosing is set individually. The main contra indications include decompensated heart failure, chronic obstructive broncho-pulmonary disease, asthma, cardiogenic shock, AV block (II-III degree), sick sinus syndrome, pheochromocytoma untreated, bradycardia, combination with parenteral administration of diltiazem or verapamil vessels, peripheral vascular disease, hereditary intolerance to lactose, glucose or galactose malabsorption. This medicament is chiefly applied with caution in patients with bronchospastic syndrome, chronic bronchitis, and emphysema. You need to make medical examination if you are planning to buy Coreg online in the best pharmacies all over the country.