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Darifenacin relates to selective antagonists of m3-cholinergic receptor. These receptors are the main subtype that controls muscle contractions of the bladder. Cystometric studies in patients with urinary bladder involuntary contractions are showed that after the treatment with preparation there was observed increase in bladder capacity, raising the threshold of non-uniform volumetric rate and decrease the frequency of irregular contractions of the detrusor. These findings are consistent with clinical observations to reduce the frequency of incontinence episodes, frequency decreases, painful urination, decreased frequency of persistent urge to urinate and an increase in functional bladder capacity. In accordance with the selective profile preparation does not cause significant adverse effects of the CNS and with the cardiovascular system (tachycardia was observed in less than 1% at all doses). As with other medications in this class, there was a dose-dependent prolongation of the passage of the content on the large intestine and decrease salivation. Darifenacin 15mg 90 pills may be ordered in different chemist's shops. Humans are indicated the medicine in order to cure overactive bladder (persistent urge to urinate, acute urinary incontinence, nocturia). Patients who have clinically significant violation of the outflow from the bladder, the risk of urinary retention, severe constipation or obstructive diseases of the gastrointestinal tract such as pyloric stenosis should apply the medication carefully. To buy Darifenacin online it is better to learn the preparation’s instructions before.
Generic name: Darifenacin
Brand name: Enablex, Emselex
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