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Depakote is an anticonvulsive medicamental remedy. This preparation renders a central muscular-relaxing and sedative action. The main active substances are Valproic acid and Valproate semisodium. These matters display an anti epileptic activity under all types of epilepsy. The main mechanism of this drug’s action ties together with some influence of valproic acid on GABA-ergic system: this medication heightens some containing of GABA in the central nervous system and activates the GABA-ergic transmission. Depakote 250mg 120pills are mostly applied by adults in view of monotherapy or in combination with other antiepileptic medications under the treatment of generalized epileptic attacks (clonic, tonic, tonic-clonic, absentia, myoclonic, atonic and so on), Lennox-Gusto’s syndrome, partial epileptic attacks (partial attacks with secondary generalization or without it), bipolar affective distributions (such medical cure as preventive measures) and some others. Children can take this medicament such in view of monotherapy as in combination with other antiepileptic drugs for treating of generalized and partial epileptic attacks, different bipolar affective disorders and many others. The contra indications are heightened sensitiveness to one of the main active matters, acute hepatitis, chronic hepatitis, heavy sicknesses of liver and kidneys, hepatic porphyria, child’s age till six years old (the risk of tablet’s hitting to the breathing passages under swallowing), gestation, lactation period, hypoproteinemia and different others. The patients can easy and free buy Depakote online through different internet-portals.