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Florinef relates to GCS with anti-inflammatory, antiallergic and immunosuppressive effect. Preparation reduces the protein amount in plasma, enhances its catabolism in muscle, the synthesis of protein (albumin) in the liver and kidneys. Medicine increases the absorption of carbohydrates from the gastrointestinal tract, the activity of glucose-6-phosphatase, which leads to glucose increasing from the liver into the blood; activates gluconeogenesis, delays Na + and water in the body, and stimulates removal of potassium. Immunosuppressive effect is due to inhibition of cytokine release from lymphocytes and macrophages. Florinef 100mcg 200 pills are indicated under replacement therapy in severe adrenal insufficiency, congenital adrenal hyperplasia with salt loss. Using high doses there is inhibition of the pituitary gland, decreased activity of the thymus and cortisol formation, activation of gluconeogenesis, negative nitrogen balance, suppression of growth in children, subcapsular cataracts, petechiae, increased intraocular pressure, erosive and ulcerative lesions of the gastrointestinal tract, menstrual irregularities cycle, edema, increased blood pressure, aseptic necrosis of bone. With caution it is prescribed for patients with ulcers in history, male, diverticulitis, the propensity to thrombosis and embolism, metastatic carcinoma, tuberculosis (possible activation process), diabetes mellitus (probably decompensation). To avoid swelling and increasing of blood pressure patients are encouraged to follow a diet with restriction of salt intake. Buy Florinef online in chemist’s shop.
Generic name: Fludrocortisone
Brand name: Floricot
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