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Probenecid relates to anti gout agents. Preparation inhibits the reabsorption of uric acid in the renal tubules and thus enhances its removal. Increasing of uriс acid excretion by the action of medicine may increase the release of uric acid from tophi in blood plasma, which in turn may cause acute attacks of gout. In addition, medicament may delay renal excretion of other drugs, increasing their concentration in the blood plasma, which allows the use of medication as an additional tool in antibiotic therapy. After patient’s oral intake remedy is completely absorbed in the gastrointestinal tract. Cmax in plasma of blood is achieved after 2-4 hours. Binding to plasma proteins is 85-95%. Probenecid 500 mg 90 pills may be ordered by sick people at any convenient time. Tablets are not intended to treat the acute attack of gout, or treatment for patients with increased excretion of uric acid kidney, renal failure or urolithiasis. Drug is excreted by the kidneys by glomerular filtration and active secretion by proximal tubules of the kidneys. In urine 75-85% of the metabolites are identified, the residual amount is excreted in the form of unchanged substance. Urinary excretion of unchanged medicine depends on pH and flow rate of urine. Usually you may apply the medication under symptomatic treatment of hyperuricemia (gouty arthritis). Individuals usually receiving this product should avoid taking aspirin. Patients with chronic renal insufficiency must take the medicament with caution. People can buy Probenecid online during all day.
Generic name: Probenecid
Brand name: Bencid, Benuryl
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