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Ranolazine covers to the antianginal preparations’ range with the same main active ingredient. This medicamental remedy is an inhibitor of late sodium ion current in myocardial cells. Reduced intracellular accumulation of sodium leads to a reduction of excess of intracellular calcium ions. This reduces intracellular ionic imbalances during ischaemia. Decreasing excess intracellular calcium promotes relaxation of the myocardium and thus lowers ventricular diastolic wall stress. The main indication for application of the preparation Ranolazine 500mg 90 pills is stable angina. The recommended starting dose for adults is 500 mg 2 times / day. After 2-4 weeks the dosage if necessary, can be increased to 1000 mg two times by day. The maximum daily dosage is 2000 mg. At appearance of collateral effects caused by drug intake (for example, dizziness, nausea, or vomiting), it is necessary to reduce to 500 mg. Then if symptoms persist, the use of the drug should be discontinued. Different adverse effects seen in patients taking the medicine, in most cases are characterized by mild or moderate severity and usually develop within the first 2 weeks of treatment: headache, constipation, vomiting, fatigue, anorexia, decreased appetite, dehydration, anxiety, insomnia, lethargy, syncope, hypoesthesia, somnolence, tremor, blurred vision, visual disturbances, noise in the ears, flushing, hypotension, dyspnoea, cough, nausea, epistaxis, abdominal pain, dry mouth, dyspepsia, flatulence, stomach discomfort, itching, rash, pain in limbs, muscle spasms, joint swelling, dysuria, hematuria, fatigue, peripheral edema. If it is necessary every sick patient can buy Ranolazine online at the lowest prices with helping of our informational internet-service.

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