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Sinemet is a combined antiparkinsonian medicamental agent. This remedy consists of two main ingredients – Carbidopa (the inhibitor of aromatic amino acids decarboxylase) and Levodopa (predecessor of dopamine). This combination of matters removes the hypokinesia, rigidity, tremor, dysphagia, salivary discharge and so on. The antiparkinsonian action of Levodopa is conditioned by its transformation into dopamine directly in the central nervous system that brings to the recruitment rate of dopamine deficit in CNS. The dopamine created in peripheral tissues doesn’t take part in realization of antiparkinsonian effect of this substance (doesn’t penetrate into the central nervous system) and it responsible for big quantity of levodopa collateral results. Other main matter is an inhibitor of peripheral dopha-decarboxylase. It brings down the formation of dopamine in peripheral tissues that indirectly brings to heightening of levodopa quantity entered to the central nervous system. The action of this preparation is manifested during the first days from the application starting. The full effect is reached during the next seven days. Sinemet 25mg/100mg 90 pills are effectively used for treating of Parkinson’s sickness and syndrome of parkinsonism with known etiology (owing to encephalitis, cerebrovascular damages, intoxication by some toxic substances including by carbon monoxide or manganese) and so on. This remedy isn’t taken under the heightened perceptibility to this preparation or its components, some skin diseases, heavy psychosis or neurosis, gestation (including breast-feeding) and others. Buy Sinemet online at the lowest price right now.