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Lithium salts relates to the medical class well-known as anti depressed remedies or antidepressants. This drug also belongs to the pharmacological group of normotimics. This medicament (normotimic agents) normalizes the psychical conditions of the patients and it doesn’t call any general deferred response. This medical preparation renders also an anti depressing, sedative and anti maniacal actions. The positive effect is made conditional on Lithium ions, which are the antagonists of sodium ions forced out them from the cells and thereby they bring down the bioelectric activity of brain’s neurons. This medicant helps in quickening of biogenic amines’ disintegration (it is lowered the concentration of serotonin and norepinephrine in brain’s tissues). The remedy heightens the apprehensibility of hippocampus neurons and other areas of brain to the dopamine’s action. Lithium 400mg 90 pills are necessary to the treatment of recurrent bipolar depressed conditions, mania, hypomania, some kinds of depressions, different recurrent affective distressed conditions, maniacal conditions of various genesis, phase processing psychosis and many others. The favourable action of these substances under the migraines can be tied together with some changes of serotonin and histamine concentration on the thrombocytes. Anti depressing action can be tied together with strengthening of serotonergic activity. So after you visit and consult with your psychiatrist you can buy Lithium online with help of our informational portal.
Generic name: Lithium
Brand name: Lithane, Lithonate, Eskalith, Eskalith-Cr, Lithobid
Introduction to Lithium
Lithium is a mood-stabilizing medication that is primarily used to treat bipolar disorder, a mental health condition characterized by extreme mood swings, including episodes of mania and depression. Lithium helps stabilize mood and reduce the frequency and severity of manic episodes.
How Lithium Works
While the exact mechanism of action of Lithium in treating bipolar disorder is not fully understood, it is believed to involve the modulation of neurotransmitter activity in the brain, particularly serotonin and norepinephrine. Lithium also affects intracellular signaling pathways and may have neuroprotective properties.
Indications for Use
Lithium is indicated for the treatment of:
- Bipolar Disorder (manic-depressive illness)
- Manic Episodes associated with Bipolar Disorder
- Maintenance treatment to prevent recurrence of bipolar mood episodes
Where to Buy Lithium Online Without Prescription: For those seeking to purchase Lithium online without a prescription, reputable internet pharmacies offer comprehensive information on the medication, including dosage instructions, potential side effects, and contraindications. Overnight delivery options may be available for added convenience.
Dosage and Administration
The dosage of Lithium varies depending on the specific condition being treated, the severity of symptoms, and individual patient factors. For acute manic episodes, the typical starting dose for adults is 600-900 mg per day, divided into two to three doses. For maintenance treatment, the usual dose range is 300-600 mg per day.
Potential Side Effects
Common side effects of Lithium may include:
- Increased thirst and urination
- Hand tremors
- Weight gain
- Nausea and vomiting
- Diarrhea or constipation
- Hair loss These side effects are usually mild and transient but should be reported to a healthcare provider if they persist or worsen over time. Serious side effects such as confusion, irregular heartbeat, seizures, or signs of lithium toxicity (e.g., vomiting, diarrhea, drowsiness, muscle weakness) require immediate medical attention.
Precautions and Warnings
Lithium should be used with caution in patients with a history of kidney disease, thyroid disorders, or heart disease, as it may exacerbate these conditions. Regular monitoring of lithium levels in the blood is essential to ensure therapeutic efficacy and prevent toxicity. Patients should maintain adequate fluid intake and avoid dehydration, as dehydration can increase the risk of lithium toxicity.
Drug Interactions
Lithium may interact with other medications, including diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and antidepressants, potentially increasing the risk of lithium toxicity or altering drug levels in the blood. It is essential to inform healthcare providers about all medications, supplements, and herbal products being taken concurrently.
Overdose and Emergency Management
In cases of Lithium overdose, immediate medical attention is necessary. Symptoms of overdose may include drowsiness, confusion, slurred speech, tremors, seizures, and coma. Treatment may involve supportive measures, gastric lavage, intravenous fluids, and hemodialysis to remove excess lithium from the bloodstream.
Conclusion
Lithium is a cornerstone treatment for bipolar disorder, helping stabilize mood and reduce the frequency of mood episodes. Online pharmacies offer convenient access to this medication, but it’s crucial to adhere to proper dosage guidelines, monitor for potential side effects, and seek medical advice if needed. By understanding Lithium’s pharmacology, indications, and precautions, patients and healthcare providers can work together to achieve optimal treatment outcomes.
Lithium - Comprehensive Usage Guide: instructions, indications, composition, side effects
Composition
- Active Ingredient: Lithium carbonate
- Excipients: May include microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate, and other inactive ingredients depending on the formulation.
Official Forms
- Tablets: Available in various strengths, including 300 mg and 600 mg tablets.
- Capsules: Available in various strengths, including 150 mg and 300 mg capsules.
Pharmacological Group
Lithium belongs to the pharmacological group of mood stabilizers (ATC code: N05AN01).
Pharmacological Properties
- Pharmacodynamics: The exact mechanism of lithium’s mood-stabilizing effects is not fully understood, but it is thought to involve modulation of neurotransmitter signaling pathways, including serotonin and norepinephrine.
- Pharmacokinetics: Lithium is absorbed in the gastrointestinal tract and distributed widely throughout the body, including the brain. It is excreted primarily by the kidneys, and its elimination half-life is approximately 24 hours.
Indications
Lithium is indicated for the treatment of:
- Bipolar disorder (manic-depressive illness), including manic and depressive episodes
- Maintenance treatment to prevent recurrence of manic and depressive episodes
Contraindications
Lithium is contraindicated in individuals with:
- Known hypersensitivity to lithium or any component of the formulation
- Severe renal impairment or conditions predisposing to lithium toxicity
- Sodium depletion or dehydration
Interactions
Lithium may interact with:
- Diuretics, ACE inhibitors, and NSAIDs, leading to increased lithium levels and toxicity
- Antidepressants, antipsychotics, and other mood stabilizers, potentially altering their efficacy or increasing the risk of adverse effects
Specifics of Use
- Lithium should be administered orally in divided doses, preferably with meals to minimize gastrointestinal side effects.
- The dosage and serum lithium levels should be monitored regularly to maintain therapeutic efficacy and prevent toxicity.
- It may take several weeks for lithium to exert its full therapeutic effects, and treatment should be continued as directed by a healthcare provider.
Pregnancy and Breastfeeding
- Lithium should be used with caution during pregnancy, especially during the first trimester, and only if the potential benefits outweigh the risks.
- Breastfeeding is not recommended during lithium treatment due to the potential risk of lithium accumulation in the infant.
Dosage and Administration
- The initial dosage of lithium for acute manic episodes is typically 600 mg to 1800 mg daily, divided into multiple doses.
- Maintenance doses range from 600 mg to 1200 mg daily, depending on individual response and serum lithium levels.
- Dosage adjustments may be necessary in elderly patients and those with renal impairment.
Overdose
In case of overdose, supportive measures should be initiated, and medical attention should be sought immediately. Symptoms of lithium toxicity may include nausea, vomiting, diarrhea, tremors, and confusion.
Side Effects
Common side effects of lithium may include:
- Polyuria, polydipsia
- Fine hand tremor
- Weight gain
- Hypothyroidism
- Cognitive impairment
Storage and Shelf Life
Lithium tablets and capsules should be stored at room temperature (15-30°C) in a dry place, protected from light and moisture. The expiration date should be checked before use.
These comprehensive instructions provide essential information on the composition, pharmacological properties, indications, contraindications, interactions, administration, side effects, and storage of Lithium, aiding healthcare professionals and patients in safe and effective medication use. Always consult a healthcare provider for personalized medical advice.