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Buy Alphagan online without prescription in Worldwide Pharmacies
Alphagan is an anti glaucomatous medicamental remedy that is representative of the alpha adrenomimetic agents. The drug is highly selective, which determines its efficiency and the minimum number of developing side effects. Because of the preparation’s usage it becomes possible to effectively reduce elevated intraocular fluid pressure. The main active ingredient is brimonidine tartrate. This component determines the therapeutic efficacy of ophthalmic medicines. The treatment is performed only locally by instillation into the conjunctival sac. A single dose is one drop, three times throughout the day. The main contraindications that restrict the use of ophthalmic agents are hypersensitivity to components of the preparation, which may develop in some patients, co-administration with inhibitors of monoamine oxidase, which are often prescribed in neurological and psychiatric practice, pregnant women; nursing mothers, children under 2 years of age. You may purchase Alphagan 5ml/0.2% 3 bottles in on-line drug-store. During the therapy there may develop as systemic and local side effects as redness and edema of the conjunctiva, slight blurred vision, sensitivity to light, pain in the head, dizziness, weakness, drowsiness, hypertension, respiratory failure, a cough, skin rash, increased cholesterol levels in the blood, violation of taste perception and some others. The simultaneous use of contact lenses is not permissible. The therapeutic effect should appear within 24-36 hours, if this does not happen, then it is necessary to consult an ophthalmologist to decide on the further application of the medicament. Many internet-pharmacies all over the country generally offer to buy Alphagan online today without anyprescriptions.
Generic name: Brimonidine
Brand name: Alphagan
Alphagan - Comprehensive Usage Guide: instructions, indications, composition, side effects
Composition
Active Ingredient: Brimonidine tartrate
Excipients: May include benzalkonium chloride, purified water, sodium chloride, and other inactive ingredients depending on the formulation.
Official Forms
Eye Drops: Available in various concentrations, including 0.1% and 0.15% brimonidine tartrate.
Pharmacological Group
Alphagan belongs to the pharmacological group of alpha-2 adrenergic agonists (ATC code: S01EA05).
Pharmacological Properties
Pharmacodynamics: Brimonidine tartrate lowers intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow.
Pharmacokinetics: Following ocular administration, brimonidine is absorbed systemically, with peak plasma concentrations reached within 1 to 4 hours. It undergoes hepatic metabolism and is excreted mainly via urine.
Indications
Alphagan is indicated for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Contraindications
Alphagan is contraindicated in individuals with:
- Hypersensitivity to brimonidine tartrate or any component of the formulation.
- Severe cardiovascular disease (e.g., severe coronary insufficiency, cardiac failure, bradycardia).
- Severe renal impairment (creatinine clearance < 30 mL/min).
Interactions
Brimonidine may interact with other medications, including:
- Monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, or other central nervous system depressants, potentially leading to additive effects on the central nervous system.
- Alpha-adrenergic agonists or sympathomimetic agents, increasing the risk of systemic side effects.
Specifics of Use
- Alphagan eye drops should be instilled into the affected eye(s) according to the prescribed dosage regimen.
- Shake the bottle well before each use and avoid touching the dropper tip to any surface to prevent contamination.
- Contact lenses should be removed before administration and may be reinserted after 15 minutes.
Pregnancy and Breastfeeding
- Alphagan should be used during pregnancy only if the potential benefits outweigh the potential risks to the fetus.
- It is not recommended during breastfeeding due to limited data on its excretion into breast milk.
Dosage and Administration
The recommended dosage is one drop of Alphagan in the affected eye(s) three times daily, approximately 8 hours apart.
Overdose
In case of overdose, supportive measures should be initiated, and medical attention should be sought immediately. Symptoms of overdose may include systemic side effects such as hypotension, bradycardia, and central nervous system depression.
Side Effects
Common side effects of Alphagan may include:
- Ocular irritation (e.g., burning, stinging, itching)
- Conjunctival hyperemia (redness)
- Blurred vision
- Dry mouth
- Fatigue
- Headache
Less common but more severe adverse reactions may include:
- Allergic reactions (e.g., rash, itching, swelling)
- Conjunctival follicles
- Conjunctival hemorrhage
- Corneal erosion
- Corneal infiltrates
- Dizziness
- Dyspnea
- Eye discharge
- Eye pain
- Foreign body sensation
- Hypersensitivity reactions (e.g., bronchospasm, anaphylaxis)
- Photophobia
- Visual disturbances
If any of these side effects persist or worsen, patients should discontinue use and consult their healthcare provider promptly. Additionally, patients should seek medical attention if they experience any signs of systemic absorption, such as changes in heart rate, blood pressure, or mental status.