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Effexor XR covers to the big class of anti depressed agents (antidepressants). The remedy influences on the out-of-balance chemicals of person’s brain which challenges the depressions or troubled conditions. The remedy is a strong inhibitor of inverse usurpation of noradrenaline and serotonin and in insignificant degree it inhibits the reverse capture of dopamine. The mechanism of its action is made conditional by preparation’s ability to exponentiate the transmission of nervous impulses in the central nervous system. Effexor XR 150 mg 90 pills is one of the most widespread dosages for whole therapeutic course. Anti depressing action of this medicament by the man is conditioned by reinforcement of neurotransmitter activity in the central nervous system. After the application inward the remedy is absorbed well and it is extensionally metabolized in the liver. After applying of once-only dosage the medication is absorbed at any rate about 92% and absolute bioavailability puts together about 45% (in consequence of presystemic metabolism). The food application doesn’t render the substantial influence by the absorption and biotransformation of this medicant. Nowadays it becomes possible and very easy to buy Effexor XR online without any prescriptions from your psychiater.
Generic name: Effexor XR
Brand name: Venlafaxine, Phenylethyl Amine, Efectine
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Before you begin to apply Effexor XR it is followed to inform your physician about some problems with health such as kidneys’ diseases, liver sicknesses, high arterial pressure, convulsions or epilepsy, bipolar impairment (maniacal depression), bipolar disturbance or self-murder in family anamnesis or thoughts about suicide. You cannot take this preparation or you need the dosage updating and special observation during whole treatment if you suffer from one of these illnesses. The medicament is mostly employed for the medical cure of all types of depressions with accompanied anxiety and also for prevention of repeated commission including application under recurrent depressing disturbances (in-patient department or in the outpatient setting). You have to buy Effexor XR without prescription overnight delivery if you have one of depressed states. There are several strict boundary conditions to application including recently transferred cardiac infarction and unstable stenocardia, sharp changes with arterial pressure, heightened intraocular pressure and narrow-angle glaucoma, manic conditions in anamnesis, initially reduced body weight, nephritic hepatic insufficiency, age till eighteen years old (the safety and effectiveness from applying don’t install).
Where can I buy Effexor XR without prescription online USA? Realizing forms and dosages
Effexor XR is realized in view of tablets. You can order Effexor XR in dosages of 37.5, 75 and 150 mg with several packages of 30, 60, 90 and 120 pills. Recommended beginning daily norm is 75 mg in one applying. Under the necessity the daily dose can be gradually heighten till maximal which consists 225 mgday. The interval between the dosages growth can make up two weeks and more but not less than four days. The patients who get these tablets with immediate release can be transfer to maximal daily norm. It is followed to remember that preparation’s daily norm must be formed individually. The medicament’s abolition is followed to lead little by little. The time for medication’s abolition is depended from the dose, duration of taken therapy and individual peculiarity of every patient. Under the treatment more than six weeks it is necessary lowering dosage till medicant’s abolition for the period not less than two weeks. The pills are recommended to use with eating approximately in the same time. You haven’t to divide, to crumble up, to chew or to dissolve in water these tablets. The patients with infringement of kidneys’ functions have to use daily dosage which is decreased by 25-50%. In some occurrences the dose can be bring down in big quantity. Where can I buy Effexor XR l without prescription online USA? Our internet-drugstore works twenty-four-hours with delivery over the country.
If you want cheap Effexor XR without a prescription it is essential to know warning and nonoperating effects
You have to stop preparation’s applying immediately and you must visit your physician if you have followed serious collateral actions such as
- some allergic reactions (difficulty in breathing, respiratory ways narrowing, edema of lips, tongue, face or eruption);
- low blood pressure (dizziness, weakness);
- high blood pressure (strong headaches, hazed vision);
- fever or shivering.
You have to continue the medication’s applying and to communicate you physician if you have
- disposition to sweating;
- foggy vision;
- sleeplessness;
- weakness;
- nausea, vomiting, diarrhea, defecatory disability;
- lowering of sexual passion, sexual feebleness or impediment in achievement of orgasm;
- dry mouth;
- tremor, irritability, uneasiness and inability to concentrate;
- changes in weight and appetite.
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Introduction to Effexor XR
Effexor XR, with the generic name venlafaxine, is an antidepressant medication that belongs to the class of serotonin-norepinephrine reuptake inhibitors (SNRIs). It works by increasing the levels of serotonin and norepinephrine, neurotransmitters that play a role in regulating mood, in the brain.
How Effexor XR Works
Effexor XR works by inhibiting the reuptake of serotonin and norepinephrine, thereby increasing their concentrations in the brain. This leads to enhanced neurotransmission and improvement in mood symptoms associated with depression and anxiety disorders.
Indications for Use
Effexor XR is indicated for the treatment of:
- Major Depressive Disorder (MDD)
- Generalized Anxiety Disorder (GAD)
- Panic Disorder
Where to Buy Effexor XR Online Without Prescription: For those looking to purchase Effexor XR online without a prescription, reputable internet pharmacies offer comprehensive information on the medication, including dosage instructions, potential side effects, and contraindications. Overnight delivery options may be available for added convenience.
Dosage and Administration
The dosage of Effexor XR varies depending on the specific condition being treated, the severity of symptoms, and individual patient factors. The typical starting dose for adults is 75 mg once daily, taken with food. This dose may be adjusted by a healthcare provider based on response and tolerability.
Potential Side Effects
Common side effects of Effexor XR may include nausea, drowsiness, dizziness, dry mouth, and constipation. These side effects are usually mild and transient but should be reported to a healthcare provider if they persist or worsen over time. Serious side effects such as suicidal thoughts or serotonin syndrome are rare but require immediate medical attention if they occur.
Precautions and Warnings
Effexor XR should be used with caution in patients with a history of bipolar disorder, seizures, or liver disease, as it may exacerbate these conditions. It should also be avoided in combination with monoamine oxidase inhibitors (MAOIs) due to the risk of serotonin syndrome. Patients should be monitored for changes in mood or behavior, especially during the initial weeks of treatment.
Drug Interactions
Effexor XR may interact with other medications, including certain antidepressants, antipsychotics, and pain medications, potentially increasing the risk of adverse effects or reducing the efficacy of either medication. It is essential to inform healthcare providers about all medications, supplements, and herbal products being taken concurrently.
Overdose and Emergency Management
In cases of Effexor XR overdose, supportive measures should be initiated as needed. Symptoms of overdose may include extreme drowsiness, seizures, and changes in heart rate. Treatment may involve gastric decontamination, symptomatic management, and close monitoring of vital signs.
Conclusion
Effexor XR is a widely prescribed medication with proven efficacy in managing depression and anxiety disorders. Online pharmacies offer convenient access to this medication, but it’s crucial to adhere to proper dosage guidelines, monitor for potential side effects, and seek medical advice if needed. By understanding Effexor XR’s pharmacology, indications, and precautions, patients and healthcare providers can work together to achieve optimal treatment outcomes.
Effexor XR - Comprehensive Usage Guide: instructions, indications, composition, side effects
Composition
- Active Ingredient: Venlafaxine hydrochloride
- Excipients: May include ethylcellulose, gelatin, hypromellose, iron oxide, magnesium stearate, cellulose, and other inactive ingredients depending on the formulation.
Official Forms
Extended-Release Capsules: Available in various strengths, including 37.5 mg, 75 mg, and 150 mg capsules.
Pharmacological Group
Effexor XR belongs to the pharmacological group of serotonin-norepinephrine reuptake inhibitors (SNRIs) (ATC code: N06AX16).
Pharmacological Properties
- Pharmacodynamics: Venlafaxine exerts its antidepressant effects by inhibiting the reuptake of serotonin and norepinephrine in the synaptic cleft, thereby increasing their neurotransmission in the central nervous system (CNS). It also has weak inhibitory effects on dopamine reuptake.
- Pharmacokinetics: Venlafaxine is well-absorbed after oral administration, with peak plasma concentrations achieved within 2 to 3 hours. It undergoes extensive hepatic metabolism via the cytochrome P450 enzyme system (primarily CYP2D6 and CYP3A4) and is excreted mainly in the urine.
Indications
Effexor XR is indicated for the treatment of:
- Major depressive disorder (MDD)
- Generalized anxiety disorder (GAD)
- Panic disorder (PD)
- Social anxiety disorder (SAD)
Contraindications
Effexor XR is contraindicated in individuals with:
- Hypersensitivity to venlafaxine or any component of the formulation
- Concomitant use of monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing MAOI therapy
- Uncontrolled narrow-angle glaucoma
- Concomitant use of thioridazine or linezolid
Interactions
Venlafaxine may interact with other medications, including:
- MAOIs, SSRIs, SNRIs, tricyclic antidepressants, and other serotonergic drugs, increasing the risk of serotonin syndrome
- Drugs that inhibit CYP2D6 enzymes, potentially increasing venlafaxine levels and toxicity
- CNS depressants, alcohol, and drugs that impair cognitive or motor function, potentiating sedation and impairment
Specifics of Use
- Effexor XR capsules should be taken orally once daily with food, preferably in the morning, as directed by a healthcare provider.
- The initial dosage for depression and anxiety disorders is typically 75 mg/day, gradually titrated to a therapeutic dose of 150-225 mg/day based on patient response and tolerability.
- Dosage adjustments should be made cautiously, with close monitoring for adverse effects, especially during initiation or dose changes.
Pregnancy and Breastfeeding
- Effexor XR should be used with caution during pregnancy, especially during the third trimester, and only if the potential benefits outweigh the potential risks to the fetus.
- Venlafaxine is excreted in breast milk, and breastfeeding is not recommended during Effexor XR treatment due to the potential risk to the infant.
Dosage and Administration
- Dosage adjustments may be necessary in patients with hepatic impairment or renal impairment to prevent drug accumulation and minimize the risk of adverse effects.
- Elderly patients may require lower initial doses and slower titration due to age-related changes in drug metabolism.
Overdose
In case of overdose, supportive measures should be initiated, and medical attention should be sought immediately. Symptoms of venlafaxine overdose may include nausea, vomiting, seizures, tachycardia, and coma.
Side Effects
Common side effects of Effexor XR may include:
- Nausea
- Headache
- Dizziness
- Somnolence
- Dry mouth
- Constipation
Storage and Shelf Life
Effexor XR capsules should be stored at controlled room temperature (20-25°C) in a dry place, protected from light and moisture. The expiration date should be checked before use.
These comprehensive instructions provide essential information on the composition, pharmacological properties, indications, contraindications, interactions, administration, side effects, and storage of Effexor XR, aiding healthcare professionals and patients in safe and effective medication use. Always consult a healthcare provider for personalized medical advice.