Buy Naprosyn online without prescription in Worldwide Pharmacies
Naprosyn relates to the class of several medicaments agents well-known as non-steroidal anti-inflammatory medications (NSAIDs). The main active component is Naproxen. It is an anti-inflammatory, anti-fever and pain-relieving substance. This preparation mainly calls some weakening or disappearing of the painful syndrome, including different pains in articulations in calming and under moving, decreasing of the morning joint stiffness and articulation swelling. The medication also is capable to increase the dimension of various movements. It successfully oppresses the aggregation of blood plates or elementary bodies. Under prolonged application the drug renders a desensitized action. Naprosyn 250mg 120 pills have different indication for this remedy’s applying such as ankylosing spondylitis, rheumatoid arthritis, articular syndrome under the podagra’s sharpening, rheumatoid arthritis (and some other types of this illness); pains in backbone, myalgia, neuralgia, traumatic inflammation of locomotive apparatus and soft tissues and some others. The medicament also can be taken as additional medicant under several infectious-inflammatory sicknesses of ENT-organs, adnexitis, primary dysmenorrhea, headache, toothache and many others. Contraindications can be presented as erosive-ulcerous lesions of gastrointestinal tract in stage of sharpening, expressed damages of the kidneys and liver’s functions, early child’s age (till one year old), heightened sensitiveness to the main active matter including to some other nonsteroidal anti-inflammatory remedies and so on. People usually buy Naprosyn online through several internet-services.
Generic name: Naproxen
Brand name: Anaprox, Naprosyn, Aleve, Synflex, Naprelan, Naprogesic, Proxen, Miranax, Xenobid
Naprosyn - Comprehensive Usage Guide: instructions, indications, composition, side effects
Composition
- Active Ingredient: Naproxen
- Excipients: May include colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, povidone, and other inactive ingredients depending on the formulation.
Official Forms
- Naprosyn is available in various formulations, including:
- Tablets: Available in strengths such as 250 mg, 375 mg, and 500 mg.
- Suspension: Available in a concentration of 125 mg/5 mL.
Pharmacological Group
- Naprosyn belongs to the pharmacological group of nonsteroidal anti-inflammatory drugs (NSAIDs), specifically propionic acid derivatives (ATC code: M01A B09).
Pharmacological Properties
- Pharmacodynamics: Naproxen exhibits anti-inflammatory, analgesic, and antipyretic properties by inhibiting prostaglandin synthesis through non-selective inhibition of cyclooxygenase (COX) enzyme activity. It primarily acts by reducing inflammation, pain, and fever associated with various conditions.
- Pharmacokinetics: Naproxen is well-absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations achieved within 2-4 hours. It undergoes extensive hepatic metabolism and is primarily excreted in the urine as metabolites.
Indications
- Naprosyn is indicated for the symptomatic relief of pain and inflammation in conditions such as:
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute gout
- Mild to moderate pain (e.g., headache, dental pain, menstrual cramps)
- Fever
Contraindications
- Naprosyn is contraindicated in individuals with:
- Hypersensitivity to naproxen or any component of the formulation
- History of allergic reactions (e.g., asthma, urticaria, angioedema) to NSAIDs, including aspirin
- Active peptic ulcer disease or gastrointestinal bleeding
- Severe heart failure
- Severe renal impairment (creatinine clearance <30 mL/min)
- Severe hepatic impairment
- Pregnancy (third trimester)
- Concomitant use with other NSAIDs or aspirin, due to the potential for additive adverse effects
Interactions
- Naprosyn may interact with various medications, including anticoagulants, antiplatelet agents, diuretics, ACE inhibitors, angiotensin II receptor blockers (ARBs), and selective serotonin reuptake inhibitors (SSRIs), potentially increasing the risk of gastrointestinal bleeding, renal toxicity, or cardiovascular events. Caution is advised when co-administering Naprosyn with these agents.
Specifics of Use
- Naprosyn tablets should be taken orally with a full glass of water, preferably with food or milk to minimize gastrointestinal irritation. The dosage and duration of therapy depend on the severity of the condition and the patient’s response to treatment.
Pregnancy and Breastfeeding
- Naprosyn should be avoided during the third trimester of pregnancy due to the potential risk of premature closure of the fetal ductus arteriosus. It is not recommended for use during breastfeeding, as naproxen may be excreted in human breast milk.
Impact on Motor Functions
- Naprosyn may cause dizziness or drowsiness in some individuals. Patients should be cautious when driving or operating machinery until they know how Naprosyn affects them.
Dosage and Administration
- The recommended dosage of Naprosyn for adults and adolescents over 12 years of age is 250-500 mg twice daily, not exceeding 1500 mg per day.
- For children aged 2-12 years, the dosage is based on body weight and should be determined by a healthcare provider.
- The suspension should be shaken well before each use and measured with an appropriate dosing device to ensure accurate dosing.
Overdose
- In case of overdose, supportive measures should be initiated as needed. Symptoms of overdose may include nausea, vomiting, abdominal pain, headache, dizziness, drowsiness, and gastrointestinal bleeding. Patients should seek medical attention if overdose is suspected.
Side Effects
- Common side effects of Naprosyn may include:
- Gastrointestinal disturbances (e.g., dyspepsia, heartburn, nausea)
- Headache
- Dizziness
- Edema
- Rash
- Serious adverse effects such as gastrointestinal ulceration, bleeding, renal impairment, cardiovascular events, and hepatotoxicity may occur rarely.
Storage and Shelf Life
- Naprosyn tablets and suspension should be stored at room temperature (20-25°C) in a dry place, protected from light and moisture. Check the expiration date on the packaging and discard any expired or unused medication.