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Prednisolone covers to synthetic analogues of hormones separated by adrenal cortex. Preparation is 4-5 times more active in comparison with cortisone and 3-4 times in comparison with the oral route hydrocortisone. Unlike cortisone and hydrocortisone, remedy causes no appreciable sodium and water retention and only slightly increases potassium excretion. The medicament has a pronounced antiexudative, anti-allergic, antishock, anti-toxic effect. Medicine’s anti-inflammatory effect is achieved mainly involving cytosolic glucocorticoid receptors. The antiproliferative effect is associated with inhibition of synthesis of nucleic acids in cells of the basal layer of the epidermis and dermis fibroblasts. Antiallergic effect of the drug is caused by a decrease of basophils, a direct inhibition of secretion and synthesis of biologically active substances. Maximum plasma concentration is achieved after 90 minutes after administration. Preparation is excreted in the urine and feces as metabolites, partly unchanged, and crosses the placental barrier and is found in small quantities in breast milk. Patient is applied Prednisolone 40 mg 180 pills under rheumatism, infectious nonspecific polyarthritis, acute lymphoblastic, infectious mononucleosis, myeloid leukemia, bronchial asthma, neurodermatitis, acute adrenal insufficiency, hemolytic anemia, acute pancreatitis, shock and collapse during surgical procedures, glomerulonephritis, atypical conjunctivitis. Most of patients are interested to buy Prednisolone online.

Generic name: Prednisolone
Brand name: Deltacortril, Deltastab, Millipred