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Aceclofenac relates to the medicamental class of nonsteroidal anti0inflammatory preparations (NSAIDs) mostly taken for pain relieving. This medicament renders an anti-inflammatory, analgesic and anti-fever action tied together with suppression of COG 1 and 2 which are generally regulated by the synthesis of prostaglandins (hormones). Aceclofenac 100mg 90 pills are successfully employed for the medical cure of various inflammatory illnesses of locomotor apparatus including rheumatoid arthritis, osteoarthrosis, psoriatic arthritis, juvenile rheumatoid arthritis, gouty arthritis, ankylosing spondylitis, Strumpell-Marie’s sickness, rheumatoid spondylarthritis, osteoarthritis, , degenerative arthritis, hypertrophic arthritis, degenerative joint illness and different others. The medication is contra indicated under erosive-ulcerous lesions of gastrointestinal tract (in phase of sharpening), gastrointestinal bleeding, “aspirin triad” (combination of bronchial asthma, recurrented nasal polyposis and paranasal sinuses and intolerance of acetylsalicinic acid and preparations of pyrazolones row), some damages of blood formation with indistinct etiology, several distributions of blood coagulation, expressed hepatic insufficiency or active sicknesses of liver, hyperpotassemia, child or teenager’s age till eighteen years old, gestation, heightened perceptibility to the main active matters and many others. You can order and buy Aceclofenac online in any time you have and need.
Generic name: Aceclofenac, Paracetamol
Brand name: Movexx Plus, Hifenac, Aertal, Asinac
Aceclofenac: Your Comprehensive Guide to Pain Relief
Welcome to our comprehensive guide on Aceclofenac, a potent nonsteroidal anti-inflammatory drug (NSAID) used for the management of pain and inflammation associated with various conditions. Whether you’re a healthcare professional seeking detailed information or a patient looking for effective pain relief options, this guide will provide valuable insights into Aceclofenac’s mechanisms of action, indications, dosing, potential side effects, precautions, and more.
Introduction to Aceclofenac
Aceclofenac is a member of the phenylacetic acid derivative class of NSAIDs, known for its potent analgesic and anti-inflammatory properties. It is available in various formulations, including tablets, capsules, and topical preparations, making it suitable for different patient populations and pain types.
How Aceclofenac Works
Aceclofenac exerts its therapeutic effects by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the synthesis of prostaglandins, which are mediators of pain and inflammation. By blocking prostaglandin production, Aceclofenac helps alleviate pain, reduce swelling, and improve joint function in conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Indications for Use
Aceclofenac is indicated for the symptomatic treatment of various painful and inflammatory conditions, including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, and postoperative pain. It is often used as a first-line therapy for musculoskeletal disorders due to its efficacy and favorable safety profile.
Buy Aceclofenac without Prescription: While Aceclofenac is available by prescription in many countries, it may be obtainable without a prescription in some regions or through online pharmacies. However, it’s essential to ensure that you’re purchasing Aceclofenac from a reputable source to ensure product quality and safety.
Dosage and Administration
The dosage of Aceclofenac varies depending on the severity of the pain, the patient’s age, medical history, and renal function. It is typically administered orally, with or without food, and dosage forms include immediate-release tablets (100 mg to 200 mg twice daily) and sustained-release formulations (200 mg once daily).
Potential Side Effects
Common side effects of Aceclofenac may include gastrointestinal disturbances such as dyspepsia, abdominal pain, nausea, and diarrhea. Other adverse effects such as headache, dizziness, skin rash, and elevated liver enzymes are less common but may occur, especially with long-term use or high doses of Aceclofenac.
Precautions and Warnings
Aceclofenac should be used with caution in patients with a history of peptic ulcer disease, gastrointestinal bleeding, renal impairment, or cardiovascular disease. It is contraindicated in individuals with hypersensitivity to Aceclofenac or other NSAIDs and should be avoided during pregnancy, especially during the third trimester.
Drug Interactions
Aceclofenac may interact with other medications, including anticoagulants, antiplatelet agents, diuretics, and angiotensin-converting enzyme (ACE) inhibitors, potentially increasing the risk of bleeding, renal toxicity, or cardiovascular events. Patients should inform their healthcare provider of all medications they are taking before starting Aceclofenac therapy.
Overdose and Emergency Management
In cases of Aceclofenac overdose, supportive measures such as gastric lavage, activated charcoal administration, and symptomatic treatment may be necessary. Patients should seek immediate medical attention if they experience severe gastrointestinal symptoms, renal impairment, or signs of hypersensitivity reactions.
Conclusion
Aceclofenac is a valuable medication for the management of pain and inflammation, offering effective relief for a wide range of musculoskeletal and inflammatory conditions. However, it is essential to use Aceclofenac judiciously and under the guidance of a healthcare professional to minimize the risk of adverse effects and complications. By understanding Aceclofenac’s pharmacology, indications, dosing, and precautions, patients and healthcare providers can work together to achieve optimal pain management outcomes.
Aceclofenac - instructions, indications, composition, side effects
Composition
Active Ingredient: Aceclofenac
Excipients: May include lactose monohydrate, microcrystalline cellulose, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, and other inactive ingredients depending on the formulation.
Official Forms
Tablets: Available in various strengths, including 100 mg and 200 mg tablets.
Solution for Injections: Available in 50 mg/ml concentration in ampules of 1 ml or 2 ml.
Pharmacological Group
Aceclofenac belongs to the pharmacological group of nonsteroidal anti-inflammatory drugs (NSAIDs), specifically a derivative of diclofenac (ATC code: M01A B16).
Pharmacological Properties
Pharmacodynamics: Aceclofenac exerts anti-inflammatory, analgesic, and antipyretic effects by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the synthesis of prostaglandins involved in pain and inflammation.
Pharmacokinetics: Following oral administration, aceclofenac is rapidly and well-absorbed from the gastrointestinal tract. It undergoes extensive metabolism in the liver and is primarily eliminated through urinary and biliary excretion.
Indications
Aceclofenac is indicated for the treatment of:
- Pain and inflammation associated with osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute musculoskeletal disorders
- Postoperative pain
Contraindications
Aceclofenac is contraindicated in individuals with a history of hypersensitivity to aceclofenac, other NSAIDs, or any component of the formulation. It should not be used in patients with active peptic ulcer disease, severe heart failure, or renal impairment.
Interactions
Aceclofenac may interact with other medications, including anticoagulants, antiplatelet drugs, diuretics, ACE inhibitors, and lithium, potentially increasing the risk of bleeding or adverse effects. Caution is advised when co-administering aceclofenac with other drugs.
Specifics of Use
Aceclofenac tablets should be taken orally with or after food to reduce the risk of gastrointestinal irritation. The dosage and duration of therapy should be individualized based on the patient’s condition, response to treatment, and risk factors for adverse effects.
Pregnancy and Breastfeeding
Aceclofenac is contraindicated during pregnancy, especially in the third trimester, due to the potential risk of fetal harm. It should be avoided in breastfeeding women, as it may be excreted in breast milk and could harm the nursing infant.
Impact on Motor Functions
Aceclofenac may cause dizziness, drowsiness, or visual disturbances in some patients. Therefore, caution is advised when driving or operating machinery, especially during the initiation of therapy or following dosage adjustments.
Dosage and Administration
The recommended dosage of aceclofenac varies depending on the indication, severity of pain, and patient factors. Healthcare providers will determine the appropriate dose and treatment duration based on clinical judgment and guidelines.
Overdose
In the event of an overdose, supportive measures should be initiated as needed. Aceclofenac overdoses may lead to symptoms such as gastrointestinal irritation, nausea, vomiting, and renal impairment. Immediate medical attention is required in cases of overdose.
Side Effects
Common side effects of aceclofenac may include gastrointestinal disturbances (e.g., dyspepsia, abdominal pain), headache, dizziness, and rash. Serious adverse effects such as gastrointestinal bleeding, cardiovascular events, and renal impairment are rare but may occur, especially with prolonged use or at high doses.
Storage and Shelf Life
Aceclofenac tablets and solution for injections should be stored at room temperature (15-30°C) in a dry place, protected from light and moisture. Keep out of reach of children. Check the expiration date on the packaging and discard any expired or unused medication.
These extended instructions provide comprehensive information on the composition, pharmacological properties, indications, contraindications, interactions, administration, side effects, storage, and usage of Aceclofenac, aiding healthcare professionals and patients in safe and effective pain management. Always consult a healthcare provider for personalized medical advice.