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Buy Isoniazid online without prescription in Worldwide Pharmacies
Isoniazid relates to the class of medicaments well-known as antitubercular preparations of the I row (antibiotics). This drug renders a bactericidal action. The medication is very active in relation to outside and inside cellular Mycobacterium tuberculosis first of all in relations to the actively dividing ones. The exact mechanism of its action is unknown. It is supposed that this medicament ties together with suppressing of mycolic acids’ synthesis containing to the structure of mycobacteria’s cellular walls. The indications of Isoniazid 200mg 90 pills for applying are the treatment of active tuberculosis’s all forms including tuberculous meningitis (in structure of combined therapy); some preventive measures of tuberculosis by those persons who are in imminent contact with sick individuals (with tuberculosis); the persons with positive skin reaction (more 5 mm) on the tuberculin and roentgenological data indicated to the not progressing tuberculosis; the children elder than four years with positive reaction on tuberculin (more than 10 mm) and heightened risk of dissemination. This medicant isn’t allocated by physicians for sick persons with epilepsy, convulsive attacks and poliomyelitis in anamnesis, distributions of liver or/and kidneys’ functions, atherosclerosis and some others. Many people with this sickness (tuberculosis) take this preparation successfully for a long time. So you can buy Isoniazid online for treating of this illness in any time you need or have.
Generic name: Isoniazid
Brand name: Isozid, Isonex, Isokin, Laniazid, Tibinil-I, Rimifon, Pycazide, Nydrazid
Isoniazid: Your Comprehensive Guide to Tuberculosis Treatment
Welcome to our detailed guide on Isoniazid, a first-line medication used in the treatment of tuberculosis (TB). Whether you’re a healthcare professional seeking in-depth knowledge or a patient looking for effective TB treatment options, this comprehensive overview will provide you with valuable insights into Isoniazid’s mechanisms of action, indications, dosage, potential side effects, precautions, and more.
Introduction to Isoniazid
Isoniazid, also known as INH, is an antibiotic medication specifically designed to treat TB infections. It works by inhibiting the synthesis of mycolic acids, essential components of the bacterial cell wall in Mycobacterium tuberculosis, the causative agent of TB. Isoniazid is available in tablet and oral solution formulations.
How Isoniazid Works
Isoniazid exerts its antimycobacterial effects by interfering with the synthesis of mycolic acids, crucial components of the bacterial cell wall in M. tuberculosis. By inhibiting the enzyme responsible for mycolic acid synthesis, Isoniazid disrupts the integrity of the bacterial cell wall, ultimately leading to bacterial death.
Indications for Use
Isoniazid is indicated for the treatment of both active and latent TB infections. It is often used in combination with other anti-TB medications to form the cornerstone of TB treatment regimens. Isoniazid is highly effective against susceptible strains of M. tuberculosis and is considered essential in TB control programs worldwide.
Buy Isoniazid without Prescription: While Isoniazid is typically available only by prescription, it may be accessible without a prescription in some regions or through online pharmacies. However, it’s essential to consult a healthcare professional before starting any TB treatment regimen.
Dosage and Administration
The dosage of Isoniazid varies depending on the type and severity of the TB infection, as well as the patient’s age, weight, and medical history. It is typically administered orally, either as a single daily dose or multiple doses per week. Dosage forms include tablets (100 mg, 300 mg) and oral solutions (50 mg/5 mL, 100 mg/5 mL).
Potential Side Effects
Common side effects of Isoniazid may include gastrointestinal symptoms such as nausea, vomiting, and abdominal pain. Other potential side effects include hepatotoxicity, peripheral neuropathy, and hypersensitivity reactions. Patients should be monitored regularly for signs of liver dysfunction, especially during long-term treatment.
Precautions and Warnings
Isoniazid should be used with caution in patients with a history of liver disease, alcoholism, or concurrent use of hepatotoxic medications. It is contraindicated in patients with known hypersensitivity to Isoniazid or any of its components. Patients should avoid consuming alcohol while taking Isoniazid, as it may increase the risk of hepatotoxicity.
Conclusion
Isoniazid remains a cornerstone of TB treatment, offering potent antimycobacterial activity and a favorable safety profile when used appropriately. By understanding Isoniazid’s mechanisms of action, indications, dosage, and precautions, patients and healthcare providers can work together to achieve optimal treatment outcomes in the management of TB infections. With proper adherence to treatment regimens and close monitoring for potential side effects, Isoniazid plays a vital role in combating the global burden of tuberculosis.
Isoniazid - Comprehensive Usage Guide: instructions, indications, composition, side effects
Composition
- Active Ingredient: Isoniazid
- Excipients: May include microcrystalline cellulose, sodium starch glycolate, magnesium stearate, and other inactive ingredients depending on the formulation.
Official Forms
- Tablets: Available in various strengths, including 100 mg and 300 mg tablets.
Pharmacological Group
Isoniazid belongs to the pharmacological group of antituberculosis agents (ATC code: J04AC01).
Pharmacological Properties
- Pharmacodynamics: Isoniazid inhibits mycolic acid synthesis in the cell wall of Mycobacterium tuberculosis, leading to bacterial cell death.
- Pharmacokinetics: Following oral administration, isoniazid is rapidly absorbed from the gastrointestinal tract. It is metabolized in the liver and excreted primarily in the urine.
Indications
Isoniazid is indicated for the treatment of tuberculosis (TB) and for the prevention of TB in individuals with latent TB infection.
Contraindications
Isoniazid is contraindicated in individuals with:
- Known hypersensitivity to isoniazid or any component of the formulation.
- Severe liver disease or a history of drug-induced hepatitis.
- Concurrent use of alcohol, as it may increase the risk of hepatotoxicity.
Interactions
Isoniazid may interact with other medications, including:
- Drugs that inhibit or induce hepatic enzymes, potentially altering plasma concentrations of isoniazid and other concomitant medications.
Specifics of Use
- Isoniazid tablets should be taken orally on an empty stomach, preferably 1 hour before or 2 hours after meals.
- The dosage and duration of therapy depend on the type and severity of TB, as well as patient factors such as age and renal function.
Pregnancy and Breastfeeding
- Isoniazid is generally considered safe for use during pregnancy, especially in cases where the benefits outweigh the risks.
- It is excreted in breast milk, but the benefits of breastfeeding may outweigh the potential risks in treated mothers with active TB.
Dosage and Administration
- Dosage adjustments may be necessary in patients with hepatic impairment to prevent drug accumulation and minimize the risk of adverse effects.
Overdose
In case of overdose, supportive measures should be initiated, and medical attention should be sought immediately. Symptoms of overdose may include nausea, vomiting, and dizziness.
Side Effects
Common side effects of isoniazid may include:
- Peripheral neuropathy
- Hepatotoxicity
- Gastrointestinal disturbances (e.g., nausea, vomiting, abdominal pain)
Storage and Shelf Life
Isoniazid tablets should be stored at room temperature (15-30°C) in a dry place, protected from light and moisture. The expiration date should be checked before use.