Stromectol - Comprehensive Usage Guide: instructions, indications, composition, side effects

• Active Ingredient: Ivermectin
• Excipients: May include lactose, microcrystalline cellulose, corn starch, magnesium stearate, and other inactive ingredients depending on the formulation.

• Tablets: Available in various strengths, typically in 3 mg tablets.

Stromectol belongs to the pharmacological group of antiparasitic agents, specifically avermectins (ATC code: P02C C04).

• Pharmacodynamics: Ivermectin exerts its antiparasitic effect by binding to glutamate-gated chloride channels in nerve and muscle cells of parasites, leading to paralysis and death. It is active against a wide range of parasites, including roundworms, threadworms, and certain ectoparasites.
• Pharmacokinetics: Following oral administration, ivermectin is well-absorbed from the gastrointestinal tract. It is distributed widely in various body tissues and fluids, achieving therapeutic concentrations in the skin and gastrointestinal tract. Ivermectin is primarily metabolized in the liver and excreted in the feces.

Stromectol is indicated for the treatment of various parasitic infections caused by susceptible pathogens, including:

• Onchocerciasis (river blindness)
• Strongyloidiasis (threadworm infection)
• Scabies
• Pediculosis (head lice and pubic lice)

Stromectol is contraindicated in individuals with a known hypersensitivity to ivermectin or any component of the formulation. It should not be used in patients with a history of severe allergic reactions to avermectins.

Stromectol may interact with various medications, including anti-seizure drugs, benzodiazepines, and anticoagulants, potentially altering their efficacy or increasing the risk of adverse effects. Caution is advised when co-administering Stromectol with such drugs.

Stromectol tablets should be taken orally with a full glass of water, on an empty stomach, and at least one hour before or two hours after a meal. It is essential to follow the prescribed dosage and duration of therapy to ensure effective treatment.

The recommended dosage of Stromectol varies depending on the type of parasitic infection and patient characteristics such as age and weight. Healthcare providers will determine the appropriate dose and treatment regimen based on clinical judgment and guidelines.

Common side effects of Stromectol may include gastrointestinal disturbances (e.g., nausea, diarrhea, abdominal pain), dizziness, headache, and rash. Serious adverse effects such as neurotoxicity and hypersensitivity reactions are rare but require medical attention if they occur.

Stromectol tablets should be stored at room temperature (20-25°C) in a dry place, protected from light and moisture. They should be kept out of reach of children and pets.

Stromectol should be used with caution in pregnant or breastfeeding women, as safety data in these populations are limited. The potential benefits of treatment should be weighed against the potential risks to the fetus or infant.

Stromectol does not typically impair cognitive or motor functions. However, patients should be cautious when driving or operating machinery, especially if they experience dizziness or other central nervous system side effects.

In the event of overdose, supportive measures should be initiated as needed. There is no specific antidote for ivermectin overdose, and treatment is primarily supportive.

Stromectol is an essential medication for the treatment of parasitic infections, offering effective relief for a wide range of conditions. By understanding its mechanisms of action, indications, dosage, and precautions, patients and healthcare providers can work together to achieve optimal treatment outcomes. Always consult a healthcare provider for personalized medical advice.