Buy Lioresal online without prescription in Worldwide Pharmacies
Lioresal relates to the medicamental class of drugs well-known as muscle relaxants with central action of their action. This preparation possesses by muscular relaxing and anti spasmodic pharmacological action. This medication suppresses the hyper tonus of skeletal muscles called by lesions of spinal brain, manifests the inhibiting action on the skin reflexes and muscles tonus. Also the amplitude of tendinous reflexes insignificantly falls down under the operation of this medicamental agent. The remedy operates on the nervous centers disposed supraspinally because under the highest dosages this preparation inhibits some functions of the central nervous system. The medicines don’t influence on the process of nervous-muscular transmission. Lioresal 25mg 90 pills are mostly taken for treating of the spastic conditions under the spinal brain’s dysfunction (injuries, traumas, neoplasms of spinal brain, lesions of neuromotor units, syringomyelia, Morvan’s illness, transverse myelitis and so on). The indications for applying are also spastic conditions under the hemorrhagic stroke, some injuries of head, meningitis, cerebral palsy, disseminated sclerosis and some others. The contra indications include hypersensitivity, epilepsy, convulsions (in anamnesis), Parkinson’s sickness, psychosis, chronic hepatic insufficiency, gestation, period of lactation and so on. You can buy Lioresal online without any prescriptions from physicians or other specialists in this area of medicine. We suggest the lowest prices of this remedy all over the country.
Generic name: Baclofen
Brand name: Kemstro, Lioresal, Baclospas, Riclofen
Lioresal - Comprehensive Usage Guide: instructions, indications, composition, side effects
Composition
- Active Ingredient: Baclofen
- Excipients: May include microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, and other inactive ingredients depending on the formulation.
Official Forms
- Tablets: Available in various strengths, including 10 mg and 20 mg tablets.
- Injectable Solution: Available for intrathecal administration.
Pharmacological Group
Lioresal belongs to the pharmacological group of skeletal muscle relaxants (ATC code: M03BX01).
Pharmacological Properties
- Pharmacodynamics: Baclofen acts as a centrally acting skeletal muscle relaxant and antispasmodic agent by inhibiting both monosynaptic and polysynaptic reflexes at the spinal level, resulting in reduced muscle spasticity and increased range of motion.
- Pharmacokinetics: Following oral administration, baclofen is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations achieved within 2 to 4 hours. It undergoes extensive metabolism in the liver and is excreted primarily in the urine.
Indications
Lioresal is indicated for the relief of muscle spasticity associated with conditions such as multiple sclerosis, spinal cord injuries, and cerebral palsy.
Contraindications
Lioresal is contraindicated in individuals with:
- Hypersensitivity to baclofen or any component of the formulation.
- History of epilepsy or seizures.
- Severe renal impairment.
- History of stroke or intracranial hemorrhage.
Interactions
Baclofen may interact with other medications, including:
- Central nervous system depressants, such as alcohol, benzodiazepines, and opioids, leading to additive sedative effects.
- Antihypertensive agents, potentially enhancing their hypotensive effects.
Specifics of Use
- Lioresal tablets should be taken orally with or without food, usually three times daily, as directed by a healthcare provider.
- The dosage and duration of therapy depend on the severity of muscle spasticity and individual patient response.
- Treatment should be initiated at a low dose and titrated gradually to minimize the risk of adverse effects.
Pregnancy and Breastfeeding
- Lioresal should be used with caution during pregnancy, especially during the first trimester, and only if the potential benefits outweigh the risks.
- It may be excreted in breast milk, so breastfeeding is not recommended during treatment with Lioresal.
Dosage and Administration
- Dosage adjustments may be necessary in patients with renal impairment to avoid drug accumulation and potential toxicity.
- Intrathecal administration of Lioresal requires specialized equipment and should be performed by healthcare professionals experienced in this technique.
Overdose
In case of overdose, supportive measures should be initiated, and medical attention should be sought immediately. Symptoms of overdose may include drowsiness, respiratory depression, hypotension, and coma.
Side Effects
Common side effects of Lioresal may include:
- Drowsiness
- Dizziness
- Fatigue
- Weakness
- Nausea
Storage and Shelf Life
Lioresal tablets should be stored at controlled room temperature (20-25°C) in a dry place, protected from light and moisture. The expiration date should be checked before use.
These comprehensive instructions provide essential information on the composition, pharmacological properties, indications, contraindications, interactions, administration, side effects, and storage of Lioresal, aiding healthcare professionals and patients in safe and effective medication use. Always consult a healthcare provider for personalized medical advice.
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